jfa journal ICFSR-2019

AND option

OR option

All issues

Back to all journals

journal articles

INCREASED NITROGEN INTAKE FOLLOWING HIP ARTHROPLASTY EXPEDITES MUSCLE STRENGTH RECOVERY

A.A. Ferrando, M.M. Bamman, S.E. Schutzler, H.J. Spencer, A.M. Dawson, R.P. Evans, R.R. Wolfe

J Aging Res Clin Practice 2013;2(4):369-375

Background: Objectives: The aim of this study was to investigate the effects of increased nitrogen intake, via amino acid supplementation, on strength and functional recovery after THA. Design: Prospective, randomized clinical trial. Setting: Academic medical center; orthopedic clinic. Participants: Patients scheduled to receive elective hip arthroplasty. Intervention: Patients were randomly assigned to receive usual care (UC; n = 8, 55 ± 7 (SD) y) or 15 g of essential amino acid supplementation 3 times per day (EAA; n = 8, 55 ± 8 y) for 8 weeks. Measurements: Leg strength (maximal voluntary contraction of the quadriceps) was measured by hand-held dynamometer, and function by 4 meter walk and a chair stand test pre-surgery, 2, and 8 weeks post-surgery. Results: Improvement in leg strength was greater in the EAA group, as was the rate of improvement from weeks 2 to 8 post-surgery. Improved strength was realized without an increase in lean mass. Both groups improved chair stand and 4 meter walk times. EAA supplementation increased total protein intake by 0.6g/kg/d (EAA 1.7 g/kg/d vs UC 1.1 g/kg/d). Conclusions: Increased nitrogen intake via amino acid supplementation improves the rate of recovery of leg muscle strength following THA. Key words: Essential amino acids, hip arthroplasty, paximal voluntary contraction, leg strength and function.

Download PDF (470.91 Ko)